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Ansomone
[Rgh]
$220.00

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Ansomone

Anhui Anke Biotechnology Co., ltd. China

10 vials

 $220 

 

Content RGH

Volume 10 vials x 4iu

group :  Human Hormone


 What is HGH (Human Growth Hormone)?

What is a Hormone?
Hormones are tiny chemical messengers that help our body do different tasks. Hormones are made up of amino acids. Hormones are produced by the endocrine glands and then sent all over the body to stimulate certain activities. For example, Insulin is a well known hormone that helps our body digest food. Our growth, digestion, reproduction and sexual functions are all triggered by hormones.

What is Human Growth Hormone?
Human Growth Hormone (HGH or hGH) is the most abundant hormone produced by the pituitary gland (pituitary is one of the endocrine glands). The pituitary gland is located in the center of the brain. HGH is also a very complex hormone. It is made up of 191 amino acids - making it fairly large for a hormone. In fact, it is the largest protein created by the Pituitary gland.

HGH secretion reaches its peak in the body during adolescence. This makes sense because HGH helps stimulate our body to grow. But, HGH secretion does not stop after adolescence. Our body continue to produce HGH usually in short bursts during deep sleep.

Growth Hormone is known to be critical for tissue repair, muscle growth, healing, brain function, physical and mental health, bone strength, energy and metabolism. In short, it is very important to just about every aspect of our life!

What is Recombinant Growth Hormone (GH)?
Recombinant Growth Hormone is GH that is synthesized in the lab. It is a biosynthetic hormone that is identical to human growth hormone, but it is synthesized in the lab. Creating an exact replicate of HGH was not an easy task.

First scientist needed to isolate HGH. Once they achieved this step they could study the DNA make-up of the protein. Scientist quickly realized making recombinant GH would be no easy task since they had to accurately reproduce a 191 amino acid hormone.

I wish I could say it was the quest to help mankind that lead to the invention of recombinant GH, but really it was money! Pharmaceutical companies knew that there was big money to be made if they could create HGH in a test tube. Scientist from the major drug companies raced to produce the 191 amino acid hormone in a test tube. While Genentech first claimed victory in 1985, it was a short lived success. The recombinant GH they made was a 190 amino acid match - they were one amino acid off from HGH. This left the door open for Eli Lilly, who in 1986 created a 191 amino acid hormone that was an identical match to the HGH produced by the pituitary gland. The drug is called Humatrope and is the most widely used recombinant growth hormone today.

What is IGF-1?
IGF-1 stands for Insulin-like Growth Factor 1. IGF-1 is also known as Somatomedin-C. As important as HGH is, it does not last long in our bloodstream. In just a few short minutes our liver absorbs HGH and converts it into growth factors. IGF-1 is the most important growth factor that is produced. So, IGF-1 is a hormone just like HGH, but it is easier to measure in the body because it stays in our bloodstream longer than HGH. You can think of HGH as the hormone that gets the ball rolling, but IGF-1 does most of the work.

What is a Secretagogue?
A secretagogue is an agent that stimulates secretion. For now that is all you need to know about these agents with a funny name, but as we move on the functions of secretagogues and HGH enhancement will become important.

What is Homeopathy?
Homeopathy is an art of healing that is based on the principle of similars. The philosophy behind this alternative medicine is the idea that "like cures like." "Traditional medicine" often incorporates this same belief. For example, a flu shot is used to prevent the flu. The shot contains small amounts of the flu virus. The idea being that likes cure likes.

It is important to note that Homeopathic remedies often use very small amounts of drugs and supplements. You are not trying to cure the problem with the active ingredients in the homeopathic remedy, you are just trying to stimulate the body to cure itself.

Package: 1 amp (4 i.u.)
Effective Dose: 2-4 I.U., 2-4 times a week

 

PRODUCT NAME
Nomenclature: Human Growth Hormone for Injection.

DESCRIPTION
rHGH is a white, loose powder. It is a kind of sterile, lyophilized formulation of recombinant human growth hormone, which has a molecular weight of 22 kilodalton, and is identical to the nature human growth hormone in amino acid sequence and three-dimension structure.

rHGH is indicated for the growth failure due to endogenous growth hormone deficiency (GHD). In recent years, it is widely used in the treatment to the burned and preservation for human aging.

PHARMACOLOGY ACTION
rHGH exerts the action of growth improvement. It can significantly stimulate the weight increase of hypophysectomized rats. Clinical trail has also demonstrated that it could significantly improve the growth velocity of children with endogenous growth hormone deficiency (GHD).

PHARMACOKINETICS
It is reported that the equal pharmacological effect could be achieved via subcutaneous (SC) or intramuscular (IM) administration. Even though SC could lead a higher concentration of GH in plasma, IM could also yield the same IGF-1 level. The absorption of GH is relatively slow. Cmax often occur at 3 ~ 5 hours after injection. Clearance of GH is via liver and kidney, the half-life of clearance is about 2 ~ 3 hours, the un-metabolized GH excreted in urea is almost immeasurable. All of the GH in circulation system exist as a complex form with GH binding protein that make the half-life of GH prolonged.

Different administration time in a day does not affect the blood GH concentration. For the sake of such a fact that the GH peak concentration often appears during slow-wave sleeping in normal physiological state, injection just before going to bed should be the best choice.

INDICATIONS
rHGH is indicated for the growth failure due to endogenous growth hormone deficiency (GHD). In recent years, it is widely used in the treatment to the burned and preservation for human aging.

USAGE
rHGH should be taken under the advice of experienced doctor. Dosage and therapeutic schedule could be individualized. The recommended dosage of rHGH is 0.1IU per kg body-weight daily SC administration just before going to bed. Injection position should be changed everyday to avoid the atrophy of adipose tissue.

When reconstitution, 2ml sterile water should be injected along the bottle wall, then swirl the its vial with a gentle rotary motion until the contents are completely dissolved, do not shake violently. The reconstituted solution of rHGH should be clear and transparent. If there was any unsoluble substance, discard it.

ADVERSE REACTIONS
Slight pain, turgescence and itch around the injection position had happened to minority patients at the beginning of administration in clinic trail of it. All of those adverse reactions were temporal and tolerable, and ceased in one or two weeks without any treatment.

Long-term and high dosage administration of rHGH may develop the antibodies in some patient. However, the antibodies concentration could be rarely up to as 2mg/l that might minimized the therapeutic effect.

CONTRAINDICATIONS
1.It is contraindicated in those children whose terminus bone had been closed.

2.It is not recommended for those patients who suffered tumor.

WARNING AND PRECAUTIONS
1.It should be taken under the directions of experienced clinical doctor.

2.While dissolving with sterile water , it should be agitated gently rather violently. The solution should be clear and transparent. If mud appears, discard it.

VIAL SIZE
In vials of 2 IU, 4 IU ,15 IU,18 IU ,etc.

Outer packed in icebox to keep in low temperature.

In Bulk lyophilized powder form(packing : 200 milligrames per bottle )

STORAGE AND SHELF LIFE
Keep at 2 ~ 8 C (Celsius degree) away from light. The valid period is 24 months from the date of freeze-drying. The reconstituted solution can be stored at 2 ~ 8 Centidegree for 48 hours, do not be frozen.



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